echelon-inc/PS48 (PDK1 Activator)/5mg/B-0360-5mg
商品编号：
B-0360
市场价：
¥6000.00
美元价：
2850.00
产品分类：
脂质代谢研究
公司分类：
Lipid_metabolism_study
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
PS48 activates phosphoinositide-dependent protein kinase 1 (PDK1) by binding exclusively to PIF-binding pocket rather than the ATP binding site.
References
1) A. Stroba et al. “3,5-Diphenylpent-2-enoic Acids as Allosteric Activators of the Protein Kinase PDK1: Structure-Activity Relationships and Thermodynamic Characterization of Binding as Paradigms for PIF-Binding Pocket-Targeting Compounds”, J. Med. Chem, 2009, 52 (15), 4683-4693
2) L.D. Spate, et al. “PS48 can replace bovine serum albumin in pig embryo culture medium, and improve in vitro embryo development by phosphorylating AKT” Molecular Reproduction & Development 2015, DOI: 10.1002/mrd.22474.
| Categories | Biochemical Reagents |
|---|---|
| Filter | Inhibitor |
| CAS Number | 1180676-32-7 |
| Molecular Formula | C17H15ClO2 |
| Molecular Weight (g/mol) | 286.75 |
| Purity | >98% |
| Storage | 4 °C or below |
品牌介绍
Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测，抑制剂筛选试剂盒
