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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > Echelon/2-Acetyl-5-tetrahydroxybutyl imidazole (THI)/10 mg/B-0031
商品详细Echelon/2-Acetyl-5-tetrahydroxybutyl imidazole (THI)/10 mg/B-0031
Echelon/2-Acetyl-5-tetrahydroxybutyl imidazole (THI)/10 mg/B-0031
Echelon/2-Acetyl-5-tetrahydroxybutyl imidazole (THI)/10 mg/B-0031
商品编号: B-0031
市场价: ¥20260.00
美元价: 9623.50
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

THI is a trace component present in the industrially produced food colorant caramel color III. It acts as an immunosuppressant by inhibiting the enzyme sphingosine 1-phosphate lyase (S1PL) which fragments S1P to hexadecenal and phosphoethanolamine. Administration of THI in drinking water to mice (50 μg/mL) resulted in decreased S1PL activity, increased S1P levels in lymphoid tissues and reduced egress of CD4+ and CD8+ T cells (lymphopenia).

Categories

Biochemical Reagents

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Inhibitor, Sphingolipid

CAS Number

94944-70-4

Molecular Formula

C9H14N2O5

Molecular Weight (g/mol)

230.2

Purity

>95%

Storage

4 °C or below

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