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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > Echelon/Sphingosine Kinase Inhibitor (SKI-II)/50 mg/B-0024
商品详细Echelon/Sphingosine Kinase Inhibitor (SKI-II)/50 mg/B-0024
Echelon/Sphingosine Kinase Inhibitor (SKI-II)/50 mg/B-0024
Echelon/Sphingosine Kinase Inhibitor (SKI-II)/50 mg/B-0024
商品编号: B-0024
市场价: ¥5300.00
美元价: 2517.50
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins.

Categories

Biochemical Reagents

Filter

Inhibitor, Sphingolipid

CAS Number

312636-16-1

Molecular Formula

C15H11ClN2OS-HCl

Molecular Weight (g/mol)

339.2

Purity

>95%

Storage

4 °C or below

品牌介绍
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