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Echelon/Sphingosine Kinase Inhibitor (SKI-II)/50 mg/B-0024

Echelon/Sphingosine Kinase Inhibitor (SKI-II)/50 mg/B-0024
商品编号:
B-0024
市场价:
¥5300.00
美元价:
2517.50
产品分类:
脂质代谢研究
公司分类:
Lipid_metabolism_study
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins.
Categories | Biochemical Reagents |
---|---|
Filter | Inhibitor, Sphingolipid |
CAS Number | 312636-16-1 |
Molecular Formula | C15H11ClN2OS-HCl |
Molecular Weight (g/mol) | 339.2 |
Purity | >95% |
Storage | 4 °C or below |
品牌介绍
Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测,抑制剂筛选试剂盒