Echelon/AS1938909 (SHIP2 Inhibitor)/25 mg/B-0343
商品编号：
B-0343
市场价：
¥7960.00
美元价：
3781.00
产品分类：
脂质代谢研究
公司分类：
Lipid_metabolism_study
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AS1938909 is a potent SHIP2 inhibitor (Ki = 0.44uM). This compound shows signficant selectivity over some related phosphatases (IC50 = 0.18uM, 21uM, >50uM for mSHIP2, hSHIP2, hPTEN respectively). It also enhances Akt phosphorylation and increases glucose consumption and uptake in L6 myotubes.
References
A Suwa, T Yamanoto et al. “Glucose metabolism activation by SHIP2 inhibitors via up-regulation of GLUT1 gene in L6 myotubes” Eur J Pharmaco, 2010, 642, 177
| Categories | Biochemical Reagents |
|---|---|
| Filter | Inhibitor, SHIP |
| CAS Number | 1243155-40-9 |
| Molecular Formula | C19H13Cl2F2NO2S |
| Molecular Weight (g/mol) | 428.28 |
| Purity | >95% |
| Storage | 4 °C or below |
品牌介绍
Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测，抑制剂筛选试剂盒
