梯队公司/AS1949490(SHIP2抑制剂)/5mg/B-0342-5mg
商品编号:
B-0342
市场价:
¥7960.00
美元价:
3781.00
产品分类:
脂质代谢研究
公司分类:
Lipid_metabolism_study
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
AS1949490 is a potent, selective SHIP2 inhibitor with IC50 of 0.62 uM for human, which shows less effect on SHIP1 or no effects on some other types of intracellular phosphatases (such as PTEN, synaptojanin, and myotubularin). This compound also activates intracellular insulin signaling pathways in the liver and displays gluconeogensis regulation and antidiabetic effects.
References
A. Suwa, T. Yamanoto, et al. “Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2”, British Journal of Pharmacology, 2009,158, 879-88.
Categories | Biochemical Reagents |
---|---|
Filter | Inhibitor, SHIP |
CAS Number | 1203680-76-5 |
Molecular Formula | C20H18ClNO2S |
Molecular Weight (g/mol) | 371.88 |
Purity | >95% |
Storage | 4 °C or below |
品牌介绍
Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测,抑制剂筛选试剂盒