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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > 梯队公司/AS1949490(SHIP2抑制剂)/5mg/B-0342-5mg
商品详细梯队公司/AS1949490(SHIP2抑制剂)/5mg/B-0342-5mg
梯队公司/AS1949490(SHIP2抑制剂)/5mg/B-0342-5mg
梯队公司/AS1949490(SHIP2抑制剂)/5mg/B-0342-5mg
商品编号: B-0342
市场价: ¥7960.00
美元价: 3781.00
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

AS1949490 is a potent, selective SHIP2 inhibitor with IC50 of 0.62 uM for human, which shows less effect on SHIP1 or no effects on some other types of intracellular phosphatases (such as PTEN, synaptojanin, and myotubularin). This compound also activates intracellular insulin signaling pathways in the liver and displays gluconeogensis regulation and antidiabetic effects.

References

A. Suwa, T. Yamanoto, et al. “Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2”, British Journal of Pharmacology, 2009,158, 879-88.


Categories

Biochemical Reagents

Filter

Inhibitor, SHIP

CAS Number

1203680-76-5

Molecular Formula

C20H18ClNO2S

Molecular Weight (g/mol)

371.88

Purity

>95%

Storage

4 °C or below

品牌介绍
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