Echelon/IC87114 (PI3-K delta inhibitor)/25 mg/B-0305
商品编号：
B-0305
市场价：
¥7160.00
美元价：
3401.00
产品分类：
脂质代谢研究
公司分类：
Lipid_metabolism_study
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
IC87114 is a specific inhibitor of PI 3-kinase δ (IC50 = 0.5 μM) with >60-fold selectivity over other isoforms (IC50: α = >100 μM, β = 75 μM, γ = 29 μM). It does not inhibit other protein kinases (p38MAPK, CHK1, cSrc, PKBα, CK1, PKCα, PKCβII) at 10 uM. PI 3-K &delta has an important role in inflammation and inhibition has been shown to impair neutrophil migration. Administration of IC87114 in a mouse asthma model decreased allergic airway inflammation.
Publications
Powered by Bioz See more details on Bioz| Categories | Biochemical Reagents |
|---|---|
| Filter | Inhibitor, PI3K |
| CAS Number | 371242-69-2 |
| Molecular Formula | C22H19N7O |
| Molecular Weight (g/mol) | 397.43 |
| Purity | >95% |
| Storage | -20 °C or below |
品牌介绍
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