Echelon/AS604850 (PI3-K gamma Inhibitor 2)/5 mg/B-0302
商品编号:
B-0302
市场价:
¥2100.00
美元价:
1102.50
产品分类:
脂质代谢研究
公司分类:
Lipid_metabolism_study
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione (AS604850) is an inhibitor of PI 3-Kγ with an IC50 = 250 nM. AS604850 is selective for the γ-isoform (IC50: PI 3-Kα = 4.5 μM, PI 3-Kβ, PI 3-Kδ > 20 μM) and shows no notable activity against a wide array of protein kinases at 1 μM.
References
1) M. Camps et al. “Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis” Nature Medicine, 2005, 11, 936-943.
Categories | Biochemical Reagents |
---|---|
Filter | Inhibitor, PI3K |
CAS Number | 648449-76-7 |
Molecular Formula | C11H7F2NO4S |
Molecular Weight (g/mol) | 287.2 |
Purity | 95% |
Storage | 4 °C or below |
品牌介绍
Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测,抑制剂筛选试剂盒