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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > Echelon/AS604850 (PI3-K gamma Inhibitor 2)/5 mg/B-0302
商品详细Echelon/AS604850 (PI3-K gamma Inhibitor 2)/5 mg/B-0302
Echelon/AS604850 (PI3-K gamma Inhibitor 2)/5 mg/B-0302
Echelon/AS604850 (PI3-K gamma Inhibitor 2)/5 mg/B-0302
商品编号: B-0302
市场价: ¥2100.00
美元价: 1102.50
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione (AS604850) is an inhibitor of PI 3-Kγ with an IC50 = 250 nM. AS604850 is selective for the γ-isoform (IC50: PI 3-Kα = 4.5 μM, PI 3-Kβ, PI 3-Kδ > 20 μM) and shows no notable activity against a wide array of protein kinases at 1 μM.

References

1) M. Camps et al. “Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis” Nature Medicine, 2005, 11, 936-943.


Categories

Biochemical Reagents

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Inhibitor, PI3K

CAS Number

648449-76-7

Molecular Formula

C11H7F2NO4S

Molecular Weight (g/mol)

287.2

Purity

95%

Storage

4 °C or below

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