Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid formed by phosphorylation of sphingosine by sphingosine kinases. S1P binds to five G-protein coupled receptors designated S1P1-5 leading to cell proliferation, motility, and has a role in regulation cell shape. In addition, S1P acts as an intracellular mediator in a receptor-independent manner regulating cell survival and Ca2+ homeostasis.
Solubility
1 mg/mL warm acetic acid0.3 mg/mL MeOH (alternately vortex for 1 min then sonicate in a bath sonicator for 10 minutes until a clear solution is obtained. Heating the solution (50-65°C) can also help with solubilization)
Bulk quantities of this product are available. Please email echelon@echelon-inc.com for more information.
Powered by Bioz See more details on Bioz| Categories | Lipids |
|---|---|
| Filter | Sphingolipid, Sphingosine 1-phosphate |
| CAS Number | 26993-30-6 |
| Molecular Formula | C18H38NO5P |
| Molecular Weight (g/mol) | 379.5 |
| Purity | 95% |
| Storage | -20 °C or below |
