BODIPY FL PI(4)P (BODIPY FL Phosphatidylinositol 4-phosphate) is a water soluble analog of PI(4)P labeled with the green fluorophore, Bodipy^®-FL at the sn-1 position.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.

Excitation/Emission

503/513 nm

Storage

-20 °C, protect from light

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1) Caromile, L. A., A. Oganesian, et al. (2010). “The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.” J Biol Chem 285(14): 10487-96.2)Rudge, S. A., D. M. Anderson, et al. (2004). “Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.” Mol Biol Cell 15(1): 24-36.3) Oganesian, A., M. Poot, et al. (2003). “Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation.” Proc Natl Acad Sci U S A 100(13): 7563-8.

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