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梯队公司/磷脂酰肌醇3,4,5-三磷酸diC16（PI（3,4,5）P3 diC16）（铵盐）/100ug/P-3916a-100ug
PI(3,4,5)P3 diC16 (Phosphatidylinositol 3,4,5-trisphosphate diC16) ammonium salt is a synthetic, purified dipalmitoyl PI(3,4,5)P3.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.
Featured in Publications
AJP – Renal Physiology, Apr 2006
AJP – Lung Cellular and Molecular Physiol, Mar 2006
Product Keywords: Dipalmitoyl Phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3 C16, PI(3,4,5)P3 C16, or PIP3
Bulk discounts available, please email echelon@echelon-inc.com for information.
| Categories | Lipids |
|---|---|
| Filter | diC16, Phosphoinositides, PI(3,4,5)P3 |
| CAS Number | 165689-82-7 |
| Molecular Formula | C41H94N4O22P4 |
| Molecular Weight (g/mol) | 1,118.5 |
| Purity | >95% |
| Storage | -20 °C or below |
