Phosphatidylinositol diC8 (PI diC8) is a synthetic, purified dioctanoyl PI.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.
Alternate Names: Dioctanoyl Phosphatidylinositol, PtdIns C8, PI C8, (8:0/8:0) PI
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Publications
1) Koharudin, L. M., W. Furey, et al. (2009). “The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).” J Biol Chem 284(35): 23697-707.
Categories | Lipids |
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Filter | diC8, Phosphoinositides, PI |
CAS Number | 105172-95-0 |
Molecular Formula | C25H46NaO13P |
Molecular Weight (g/mol) | 608.59 |
Storage | -20 °C or below |