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当前位置: 首页 > 产品中心 > > Echelon/Cathepsin L Inhibitor (RKLLW-NH2)/5 mg/866-23
商品详细Echelon/Cathepsin L Inhibitor (RKLLW-NH2)/5 mg/866-23
Echelon/Cathepsin L Inhibitor (RKLLW-NH2)/5 mg/866-23
Echelon/Cathepsin L Inhibitor (RKLLW-NH2)/5 mg/866-23
商品编号: 866-23
市场价: ¥1820.00
美元价: 955.50
产地: 美国(厂家直采)
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产品分类: 其他
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联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

CAS Number: 289480-71-3Molecular Weight: 713.47Salt Form: TFAPurity: >96%Sequence (3-letter): Arg-Lys-Leu-Leu-Trp-NH2Sequence (1-letter): RKLLW-NH2Storage: -20 °C or below

Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition, extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for  cancer progression. The inhibitor has a low micromolar IC50.

References:1) A. Brinker, et al. (2000) “Highly potent inhibitors of human cathepsin L identified by screening combinatorial pentapeptide amide collections” Eur. J. Biochem. 267, 5085-5092.

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Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测,抑制剂筛选试剂盒