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商品详细Echelon/2-Furoyl-LIGRL-Amide (Protease-Activated Receptor 2 (PAR2) Agonist)/5 mg/873-11
Echelon/2-Furoyl-LIGRL-Amide (Protease-Activated Receptor 2 (PAR2) Agonist)/5 mg/873-11
Echelon/2-Furoyl-LIGRL-Amide (Protease-Activated Receptor 2 (PAR2) Agonist)/5 mg/873-11
商品编号: 873-11
市场价: ¥1520.00
美元价: 798.00
产地: 美国(厂家直采)
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产品分类: 其他
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联系Q Q: 3392242852
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商品介绍

Molecular Weight: 663.41Salt Form: TFAPurity: >95%Sequence (3-letter): 2-Furoyl-Leu-Ile-Gly-Arg-Leu-NH2Sequence (1-letter): (2-Furoyl)LIGRL-NH2Storage: -20 °C or below

2-Furoyl-LIGRL-NH2 is a potent agonist of Protease-Activated Receptor 2 (PAR2). Treatment of mice with 2-Furoyl-LIGRL-NH2 resulted in gastric mucosal cytoprotective activity, the potency being much greater than SLIGRL-NH2 in combination with amastatin. Capsaicin pretreatment inhibited the cytoprotective activity. 2-Furoyl-LIGRL-NH2 treatment also prevented gastric mucosal lesions in mice.

Reference: Br J Pharmacol. 2005 Jan; 144(2): 212–219.

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