LysoPC is generated through hydrolysis of the sn-2 acyl chain of PC by phospholipase A2. It is a major component of oxidized low-density lipoprotein and is believed to have an important role in inflammatory diseases and atherosclerosis. LysoPC is the substrate for Autotaxin/LysoPLD generating lysophosphatidic acid which has an important role in cell motility. The biotin 18:0 LysoPC analog is biotinylated at the end of the sn-1 acyl chain and can be used for binding to streptavidin-coated surfaces such as beads, plates, etc.
References
Matsumoto, T., Kobayashi, T., Kamata, K., (2007) Role of lysophosphatidylcholine (LPC) in atherosclerosis. Curr. Med. Chem. 14, 3209-3220
| Categories | Lipids |
|---|---|
| Filter | Biotinylated, Lysophospholipid, Phosphatidylcholine |
| Molecular Formula | C36H69N4O9PS |
| Molecular Weight (g/mol) | 765.0 |
| Storage | -20 °C or below |
