Echelon/Ac-Ile-Glu-Pro-Asp-AMC (Caspase 8/Granzyme B Substrate)/25 mg/860-69
商品编号:
860-69
市场价:
¥10220.00
美元价:
4854.50
产品分类:
其他
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
CAS Number: 216757-33-4Molecular Weight: 671.28Salt Form: N/APurity: >96%Sequence (3-letter): Ac-Ile-Glu-Pro-Asp-AMCSequence (1-letter): Ac-IEPD-AMCStorage: -20 °C or below
Ac-Ile-Glu-Pro-Asp-AMC is a fluorogenic substrate for caspase-8 and granzyme B. Caspase 8 is a cysteine protease involved in apoptosis induced by Fas and other stimuli. It is an attractive therapeutic target for a variety of degenerative disorders. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates a number of caspases involved in apoptosis.
Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.
Categories | Peptides |
---|---|
Filter | Caspase, Enzyme Substrates |
品牌介绍
Echelon产品线★合成磷脂、磷酸肌醇、鞘脂及其衍生物★脂蛋白质相互作用工具★脂质含量检测试剂盒★脂质相关生物酶活性检测,抑制剂筛选试剂盒