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当前位置: 首页 > 产品中心 > lipid > Echelon/PI(4,5)P2 diC8/1 mg/P-4508
商品详细Echelon/PI(4,5)P2 diC8/1 mg/P-4508
Echelon/PI(4,5)P2 diC8/1 mg/P-4508
Echelon/PI(4,5)P2 diC8/1 mg/P-4508
商品编号: P-4508
市场价: ¥7520.00
美元价: 3572.00
产地: 美国(厂家直采)
公司:
产品分类: 脂类
公司分类: lipid
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Phosphatidylinositol 4,5-bisphosphate diC8 (PI(4,5)P2 diC8) is a synthetic, purified dioctanoyl PI(4,5)P2.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).


Alternate Names: D-myo-Phosphatidylinositol 4,5-bisphosphate, Dioctanoyl Phosphatidylinositol 4,5-bisphosphate, PtdIns(4,5)P2 C8, PI(4,5)P2 C8, or PIP2

Bulk discounts available, please email echelon@echelon-inc.com for information.

Publications

1) Jenco, J. M., A. Rawlingson, et al. (1998). “Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins.” Biochemistry 37(14): 4901-9.2) Campbell, R. B., F. Liu, et al. (2003). “Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphate.” J Biol Chem 278(36): 33617-20.3) Haider, S., A. I. Tarasov, et al. (2007). “Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.” EMBO J 26(16): 3749.4) Lewis, A. E., L. Sommer, et al. (2011). “Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction.” Mol Cell Proteomics 10(2): M110 003376.

Categories

Lipids

Filter

diC8, Phosphoinositides, PI(4,5)P2

CAS Number

204858-53-7

Molecular Formula

C25H44Na5O19P3

Molecular Weight (g/mol)

856.48

Purity

>95%

Storage

-20 °C or below

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